Borgs are giant genetic elements with potential to expand metabolic capacity | Nature

Borgs are remarkably large, divergent archaeal extrachromosomal elements with metabolic genes linked to the methane cycle.

Download PDF Subjects Climate-change mitigation Metagenomics Abstract Anaerobic methane oxidation exerts a key control on greenhouse gas emissions 1 , yet factors that modulate the activity of microorganisms performing this function remain poorly understood. Here we discovered extraordinarily large, diverse DNA sequences that primarily encode hypothetical proteins through studying groundwater, sediments and wetland soil where methane production and oxidation occur. Four curated, complete genomes are linear, up to approximately 1 Mb in length and share genome organization, including replichore

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