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Treatment of knee osteoarthritis with acupuncture combined with Chinese herbal medicine: a systematic review and meta-analysis - Yang - Annals of Palliative Medicine

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Contributions: (I) Conception and design: F Yang, Y Li; (II) Administrative support: Y Li; (III) Provision of study materials or patients: F Yang, Y Chen, Z Lu; (IV) Collection and assembly of data: F Yang, W Xie, S Yan; (V) Data analysis and interpretation: F Yang, J Yang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Background: Many studies have demonstrated that acupuncture combined with Chinese herbal medicine (CHM) effectively treats knee osteoarthritis (KOA), with few side effects. However, few systematic reviews have offered evidence-based support. Here we conducted a meta-analysis on the combination of acupuncture with CHM in treating KOA. Methods: Databases including CNKI, Wanfang, VIP, PubMed, EMBASE, and Cochrane library were systematically searched for articles on the treatment of KOA by acupuncture combined with CHM from the establishment of the database to May 2021. Three researchers independently searched, screened, extracted, an

Introduction Osteoarthritis (OA) is a chronic degenerative disease that affects approximately 10% of men and 18% of women worldwide. The incidence of OA is increasing annually, along with increased aging. About 60-65% of people over 60 years of age suffer from symptomatic OA, of which 80% of patients present with symptoms including joint stiffness and limited range of motion, which seriously affects the quality of life of the victims ( 1 , 2 ). Even worse, an increasing proportion of young adults have also suffered from OA. OA is a heterogeneous disease caused by multiple factors and character

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