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Physiological consequences of increased dead space | Deranged Physiology

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This chapter is most relevant to the third and last part of Section F6(iv) from the 2023 CICM Primary Syllabus, which expects the exam candidates to be able to "describe the physiological impact of increased dead space". This is a highly examinable topic which has come up twice in the past papers: This is a fairly narrow topic, and can be summarised easily: The section from the 8th edition of Nunn's (p.123) which deals with this topic is relatively short, but that appears to be all that is required to answer CICM primary exam questions. At a fundamental level, increasing the dead space functionally indistinguishable from hypoventilation: Theoretically, it should not matter which dead space component has increased: this effect would be the same. However, functionally there may be some differences. Consider: let's say you have a patient who is breathing comfortably with tidal volumes of 500ml, of which there is 150ml of total dead space which is all anatomical. Let's say you have now i

Physiological consequences of increased dead space | Deranged Physiology Physiological consequences of increased dead space Ventilation-Perfusion Relationships Global and regional ventilation and perfusion West's zones of the lung Ventilation-perfusion matching and mismatching Methods of measuring ventilation-perfusion mismatch Effects of ventilation-perfusion mismatch on gas exchange Dead space and its components Measurement of dead space Physiological consequences of increased dead space The concepts of venous admixture and shunt Measurement and estimation of shunt Physiological consequ

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