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Cerebral metabolic demand | Deranged Physiology

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This is a discussion of the metabolic requirements of normal neurological function, as well as the influences on these requirements in unusual physiological circumstances. It is interesting and educational, and furthermore elements of it appear in Oh's Manual, making it a likely target for future questions. Specific questions regarding this material are more likely to appear in the primaries. The fellowship candidates are more likely to dip into this as a part of the "rationale" section in questions which ask them to critically evaluate some aspect of exotic neuromonitoring. In summary: In physiology textbooks, a consistent generalisation appears - that the human brain demands high octane fuel in the form of oxygen and glucose. Clarke & Sokoloff (1999) give an excellent short-form rundown of this in their chapter for Basic Neurochemistry, 6th ed. In short, the generalisation is accurate. The brain, under most normal circumstances, will preferentially use aerobic glucose metabolism and

Cerebral metabolic demand | Deranged Physiology Cerebral metabolic demand Intracranial hypertension Methods of intracranial pressure monitoring Indications for intracranial pressure monitoring Cerebral metabolic demand Interpretation of intracranial pressure waveforms Correlation of ICP waveforms with intracranial pathology Previous chapter: Indications for intracranial pressure monitoring Next chapter: Interpretation of intracranial pressure waveforms All SAQs related to this topic All vivas related to this topic By Alex Yartsev - 30/06/2015 Last updated 13/08/2020 - 20:24 This is a discussio

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