Doctoral research on the directed evolution of material-making microbes
Over the last 4.5 billion years, selective pressure from the environment has driven the natural evolution of microorganisms into species adapted to thrive in every corner of our planet. Inspired by this natural selection process, directed evolution approaches have also been utilized to obtain microbial strains with technologically relevant phenotypes. An example of a phenotype of interest is the bio-synthesis of sustainable materials by functional bacteria under environmentally friendly conditions. Utilize a droplet microfluidic platform for the directed evolution of functional microorganisms and investigate genotype-phenotype correlations of selected strains compared to native species. The project will involve the design and fabrication of microfluidic devices, the directed evolution and sorting of microorganisms under selective pressure, as well as the characterization of the biological activity and the genetic analysis of selected microbial strains. We look forward to receiving your
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