Modelling the pyrenoid-based CO2-concentrating mechanism provides insights into its operating principles and a roadmap for its engineering into crops | Nature Plants
To enhance CO2 fixation, algae concentrate CO2 in an organelle called the pyrenoid. A biophysical model provides systematic analysis of the mechanism and determines the minimal steps for its engineering into crops to enhance yields.
Download PDF Subjects Biological models Plant biotechnology Abstract Many eukaryotic photosynthetic organisms enhance their carbon uptake by supplying concentrated CO 2 to the CO 2 -fixing enzyme Rubisco in an organelle called the pyrenoid. Ongoing efforts seek to engineer this pyrenoid-based CO 2 -concentrating mechanism (PCCM) into crops to increase yields. Here we develop a computational model for a PCCM on the basis of the postulated mechanism in the green alga Chlamydomonas reinhardtii . Our model recapitulates all Chlamydomonas PCCM-deficient mutant phenotypes and yields general biophysi
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