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R-loop

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An R-loop is a three-stranded nucleic acid structure, composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA. R-loops may be formed in a variety of circumstances and may be tolerated or cleared by cellular components. The term "R-loop" was given to reflect the similarity of these structures to D-loops; the "R" in this case represents the involvement of an RNA moiety.

R-loop - Wikipedia Jump to content From Wikipedia, the free encyclopedia Three-stranded nucleic acid structure Schematic representation of factors promoting R-loop formation and stabilization An R-loop is a three-stranded nucleic acid structure, composed of a DNA:RNA hybrid and the associated non-template single-stranded DNA. R-loops may be formed in a variety of circumstances. They may be tolerated or cleared by cellular components. The name reflects the similarity of these structures to D-loops ; the "R" in this case represents the involvement of an RNA moiety . In the laboratory, R-loops ca

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