✳flâneur — a map of the web's best reading

Histone code - Wikipedia

en.wikipedia.org · 2,019 words · saved by 1 readers

The histone code is a hypothesis that the transcription of genetic information encoded in DNA is in part regulated by chemical modifications (known as histone marks) to histone proteins, primarily on their unstructured ends. Together with similar modifications such as DNA methylation it is part of the epigenetic code.[1] Histones associate with DNA to form nucleosomes, which themselves bundle to form chromatin fibers, which in turn make up the more familiar chromosome. Histones are globular proteins with a flexible N-terminus (taken to be the tail) that protrudes from the nucleosome. Many of the histone tail modifications correlate very well to chromatin structure and both histone modification state and chromatin structure correlate well to gene expression levels. The critical concept of the histone code hypothesis is that the histone modifications serve to recruit other proteins by specific recognition of the modified histone via protein domains specialized for such purposes, rather t

Histone code - Wikipedia Jump to content From Wikipedia, the free encyclopedia Proposed biochemical transcription of genetic information The histone code is a hypothesis that the transcription of genetic information encoded in DNA is in part regulated by chemical modifications (known as histone marks ) to histone proteins, primarily on their unstructured ends. Together with similar modifications such as DNA methylation it is part of the epigenetic code . [ 1 ] Histones associate with DNA to form nucleosomes , which themselves bundle to form chromatin fibers, which in turn make up the more fami

Explore this link on the map →

related reading