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NAD+ metabolism and its roles in cellular processes during ageing - PMC

pmc.ncbi.nlm.nih.gov · 27,253 words · saved by 1 readers

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme for redox reactions, making it central to energy metabolism. NAD+ is also an essential cofactor for non-redox NAD+-dependent enzymes, including sirtuins, CD38 and poly(ADP-ribose) polymerases. ...

Nat Rev Mol Cell Biol . Author manuscript; available in PMC: 2021 Mar 16. Published in final edited form as: Nat Rev Mol Cell Biol. 2020 Dec 22;22(2):119–141. doi: 10.1038/s41580-020-00313-x NAD + metabolism and its roles in cellular processes during ageing Anthony J Covarrubias Anthony J Covarrubias 1 Buck Institute for Research on Aging, Novato, CA, USA. 2 UCSF Department of Medicine, San Francisco, CA, USA. 3 These authors contributed equally: Anthony J Covarrubias, Rosalba Perrone, Alessia Grozio. Find articles by Anthony J Covarrubias 1, 2, 3 , Rosalba Perrone Rosalba Perrone 1 Buck Insti

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