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Chronic inflammation in the etiology of disease across the life span | Nature Medicine

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Systemic chronic inflammation increases with age and is linked to the development of several diseases, as presented in this Perspective.

Subjects Cancer Cultural evolution Evolutionary genetics Inflammation Translational immunology Abstract Although intermittent increases in inflammation are critical for survival during physical injury and infection, recent research has revealed that certain social, environmental and lifestyle factors can promote systemic chronic inflammation (SCI) that can, in turn, lead to several diseases that collectively represent the leading causes of disability and mortality worldwide, such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease and

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