✳flâneur — a map of the web's best reading

A synthetic oscillatory network of transcriptional regulators | Nature

nature.com · 294 words · saved by 1 readers

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Advertisement Nature volume 403, pages 335–338 (2000)Cite this article 93k Accesses 4151 Citations 141 Altmetric Metrics details Networks of interacting biomolecules carry out many essential functions in living cells1, but the ‘design principles’ underlying the functioning of such intracellular networks remain poorly understood, despite intensive efforts including quantitative analysis of relatively simple systems2. Here we present a complementary approach to this problem: the design and construction of a synthetic network to implement a particular function. We used three transcriptional repressor systems that are not p

Abstract Networks of interacting biomolecules carry out many essential functions in living cells 1 , but the ‘design principles’ underlying the functioning of such intracellular networks remain poorly understood, despite intensive efforts including quantitative analysis of relatively simple systems 2 . Here we present a complementary approach to this problem: the design and construction of a synthetic network to implement a particular function. We used three transcriptional repressor systems that are not part of any natural biological clock 3 , 4 , 5 to build an oscillating network, termed the

Explore this link on the map →

related reading