書豪 劉
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- Anemia: Lesson 4 - Clues from the blood smear - YouTube1 savers
- Curius / Onboarding2704 savers
- Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMC1 savers
- Solid pseudopapillary neoplasm of the pancreas: Management and long-term outcome - European Journal of Surgical Oncology1 savers
- Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMC1 savers
- Symptomatic Intracranial Hemorrhage following Intravenous Thrombolysis for Acute Ischemic Stroke: A Critical Review of Case Definitions - FullText - Cerebrovascular Diseases 2012, Vol. 34, No. 2 - Karger Publishers1 savers
- Brain Iron Detected by SWI High Pass Filtered Phase Calibrated with Synchrotron X-Ray Fluorescence - PMC1 savers
- Delirium1 savers
highlights · 43
The overall 5-year survival rate of patients with SPN is about 95%.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCmalignant SPNs: gross capsular invasion; histologic findings of high nuclear grade, cellular pleomorphism, venous invasion and necrobiotics; and immunohistochemistry findings of expression of Ki-67.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCurgery is the treatment of choice even in the cases of distant hepatic metastasis or local recurrence, which are not contraindications for surgical therapy
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCwell-marginated, large, encapsulated, solid and cystic, with areas of hemorrhagic degeneration, as revealed by high signal intensity on T1-weighted imaging and progressive peripheral or slightly heterogeneous contrast enhancement
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCCT has inherent limitations in showing certain tissue characteristics, such as hemorrhage, cystic degeneration or the integrity of the tumour capsule, that would be suggestive of SPN.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCno enhancement of the cystic portions but slight enhancement of the solid portions in the arterial phase and marked enhancement in the portal venous phase
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCcytoplasmic/nuclear accumulation of β-catenin and frequent expression of cyclin-D1 and that tumour size was closely related to microscopic features of malignant potential and apparently has an inverse relation with the expression of cyclin-D1 and Ki-67
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCNSE, vimentin and AAT may be effective indicators of SPN
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCNegative CgA and Syn staining essentially rules out an islet cell neoplasm, whereas a negative keratin stain excludes acinar carcinoma.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCsolid, pseudopapillary and cystic regions. The neoplastic cells are uniform and polygonal with abundant cytoplasm and contain oval, regular nuclei.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMC“indescribable” abdominal distension
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCliver, regional lymph nodes, mesentery, omentum and peritoneum
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCTumour recurrence is a distinct possibility after surgery and mandates routine follow-up with imaging
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCFrantz’s tumour, solid and cystic acinar tumour, papillary epithelial neoplasm, and solid and papillary epithelial tumour or neoplasm.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCvimentin, alpha-1-antitrypsin (AAT) and neuron specific enolase (NSE), spotted expressed chromogranin (CgA) and synaptophysin (Syn).
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCheterogeneous hyperintensity of the tumour on T1-weighted images with a higher T2 signal and patchy enhancement of the internal part of the tumour.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCclear-bordered cystic or cystic–solid mass with heterogeneous density in all 24 patients and satellite calcification around the mass in 4 (16.7%) patients
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMChypoechoic, clear-bordered cystic or cystic–solid mass in all 24 patients and capsular integrity in 16 (66.7%) patients.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCwith a palpable abdominal mass being the second most common symptom
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCvague abdominal pain was the most common symptom
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCwas defined by the World Health Organization (WHO) in 1996 as “solid pseudopapillary tumours” of the pancreas.
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases - PMCSPNs are low-grade tumors with a good prognosis. Margin-negative surgical resection is curative in most patients. However, almost 15% of patients demonstrate malignant features including invasion of adjacent organs or metastatic disease. Patients with malignant disease are still expected to have long survival, and aggressive surgical approach is advocated.
Solid pseudopapillary neoplasm of the pancreas: Management and long-term outcome - European Journal of Surgical OncologySurgery is the treatment of choice, even in the case of distant hepatic metastasis or local recurrence
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMChypervascular, well-encapsulated, round tumors with mixed cystic and solid components
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCpositive for α1-antitrypsin, CD56, CD10, and vimentin
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCsolid to cystic components with cellular degenerative changes
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCpancreatic body and tail
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCliver and the omentum
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCmalignancy can occur in about 15% of cases, manifesting as metastases or invasion of adjacent structures
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCThe male to female ratio is 1:10 and the mean age at presentation is 22 years.
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMC1% of all tumors of the pancreas
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCacinar, endocrine, ductal and progenitor cells have been postulated as possible beginnings of this tumor.
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCwell encapsulated mass, with low malignant potential.
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCcells positive for markers including beta-catenin, vimentin, alpha 1 antitrypsin
Solid pseudopapillary tumor: a rare neoplasm of the pancreas - PMCSymptomatic intracranial hemorrhage (SICH)
Symptomatic Intracranial Hemorrhage following Intravenous Thrombolysis for Acute Ischemic Stroke: A Critical Review of Case Definitions - FullText - Cerebrovascular Diseases 2012, Vol. 34, No. 2 - Karger PublishersThe phase shift Δφ was found to vary linearly with iron concentration with the best correspondence found in regions with high iron content.
Brain Iron Detected by SWI High Pass Filtered Phase Calibrated with Synchrotron X-Ray Fluorescence - PMCalmost two- thirds of adults over 65 years of age who were admitted to an inpatient medical or geriatric service had subsyndromal delirium
Delirium4% to almost 50% in critically ill children and adolescents 30
Deliriumhe prevalence of delirium after surgery ranges from low single- figure percentages in medically well patients undergoing minor elective surgery to ≥20% in high- risk patients undergoing major surgery, especially under emergency condition
DeliriumAcute encephalopathy is not a clinical syn- drome; rather, it is defined as a rapidly developing (usu- ally within hours to a few days), diffuse pathobiological process that might manifest as delirium or, in cases of severely decreased levels of consciousness, as coma.
DeliriumDelirium is defined as the clinical state characterized by a combination of features defined by standard diagnostic systems, such as the Diagnostic and Statistical Manual of Mental Disorders, 5th edition
Deliriumhe best management strategies are multidomain interventions that focus on treating precipitating conditions, medication review, managing distress, mitigating complications and maintaining engagement to environmental issues
Deliriumeuroinflammation, brain vascular dysfunction, altered brain metabolism, neurotransmitter imbalance and impaired neuronal network connectivity.
Delirium