Genome modelling and design across all domains of life with Evo 2 | Nature
Evo 2 is an artificial intelligence-based biological foundation model trained on 9 trillion DNA base pairs spanning all domains of life that predicts functional properties from genomic sequences and provides a rich generative model for researchers in biology.
Download PDF Subjects Evolutionary biology Genomics Machine learning Abstract All of life encodes information with DNA. Although tools for genome sequencing, synthesis and editing have transformed biological research, we still lack sufficient understanding of the immense complexity encoded by genomes to predict the effects of many classes of genomic changes or to intelligently compose new biological systems. Artificial intelligence models that learn information from genomic sequences across diverse organisms have increasingly advanced prediction and design capabilities 1 , 2 . Here we introduc
related reading
- Evo 2 Can Design Entire Genomesasimov.press
- Evo 2: DNA Foundation Model | Arc Institutearcinstitute.org
- Evo 2 Can Design Entire Genomesasimov.press
- Evo 2: DNA Foundation Model | Arc Institutearcinstitute.org
- A socratic dialogue over the utility of DNA language models (Part 1 of 2)owlposting.com
- A socratic dialogue over the utility of DNA language models (Part 1 of 2)owlposting.com
- A socratic dialogue over the utility of DNA language models (Part 1 of 2)substack.com
- A socratic dialogue over the utility of DNA language models (Part 1 of 2)owlposting.com
- A socratic dialogue over the utility of DNA language models (Part 2 of 2)owlposting.com
- Advancing regulatory variant effect prediction with AlphaGenomenature.com
- Disease variant prediction with deep generative models of evolutionary data | Naturenature.com
- AlphaGenome: AI for better understanding the genome — Google DeepMinddeepmind.google