Dr. Wei Min Lab | Columbia University
Rapid advances in light microscopy have revolutionized our ability to study biological systems at the microscopic level. New physical instrumentation, chemical innovations and biological discoveries are constantly emerging. The central goal of our research group is to discover novel principles of optical imaging by exploring the interface between physics, chemistry, chemical biology, engineering and data science, and then apply these advanced technologies to address important areas in life sciences such as brain imaging, tumor metabolism and metabolic diseases. Meanwhile, we are also pushing these powerful technology into industrial, medical and clinical applications. Chemical bonds are inherent targets for optical spectroscopy, offering power spectroscopic contrast for chemical imaging. Stimulated Raman scattering (SRS) microscopy has emerged as a highly sensitive and specific vibrational imaging technique. When the energy gap between two lasers (pump beam and Stokes beam) is resonant