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Brain–computer interface restores naturalistic speech to a man with ALS | Nature Reviews Neurology

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A voice-synthesis neuroprosthesis based on a brain–computer interface has restored instantaneous, natural-sounding speech to a man with amyotrophic lateral sclerosis.

Research Highlight Published: 08 July 2025 Motor neuron disease Heather Wood1 Nature Reviews Neurology volume 21, page 409 (2025) Cite this article 853 Accesses 3 Citations 3 Altmetric Metrics details A voice-synthesis neuroprosthesis based on a brain–computer interface (BCI) has restored instantaneous, natural-sounding speech to a man with amyotrophic lateral sclerosis (ALS), according to a new report in Nature. The study participant was BrainGate2 participant T15, a man with ALS who had some residual speaking ability but had difficulty producing intelligible speech. The research…

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