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Retatrutide hits 28% weight loss in Phase 3

chamath.substack.com · 820 words · saved by 1 readers

A summary of the interesting content that I consumed this past week…

What I Read This Week: a summary of the content that I consumed this past week… Caught My Eye… 1) Retatrutide hits 28% weight loss in Phase 3 On May 21, Eli Lilly released Phase 3 results for retatrutide from the 2,339-patient TRIUMPH-1 obesity trial. On average, with a 12mg dose, participants lost 28.3% of body weight (70.3 lbs) over 80 weeks against 2.2% on placebo (5.5 lbs). 65.3% dropped below the obesity cutoff of a 30 BMI, and 45.3% of the cohort hit at least 30% weight loss. This is comparable to bariatric surgery, which removes part of the stomach to help patients eat less and…

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