Xenotransplant regulatory and welfare considerations - Claude
I'd like a rigorous, calibrated assessment of a set of empirical and ethical claims about a proposed class of research animal. Reason from the primary literature and from first principles. Don't soften in either direction, and keep separate what is established, what is contested, and what is unknown PASTED I'll research the current landscape before answering, since several of these threads (xenotransplant status, NHP supply, regulatory trajectory, and whether this maps to a specific real-world proposal) have moved recently. I don't recognize this as a specific published macaque proposal. I do recognize its immediate ancestor: the March 2025 MIT Technology Review piece by Carsten Charlesworth, Henry Greely, and Hiromitsu Nakauchi proposing human "bodyoids" — bodies made from stem cells, using established genetic techniques to inhibit brain development, aimed at organ shortage, drug testing, and reduced animal use. Your macaque version is the same argument one species down, where regulat