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Prader-Willi syndrome: MedlinePlus Genetics

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Prader-Willi syndrome is a complex genetic condition that affects many parts of the body. Explore symptoms, inheritance, genetics of this condition.

Prader-Willi syndrome Description Prader-Willi syndrome is a complex genetic condition that affects many parts of the body. In infancy, this condition is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. Beginning in childhood, affected individuals develop an extreme hunger, which leads to chronic overeating (hyperphagia) and obesity. Some people with Prader-Willi syndrome, particularly those with obesity, also develop type 2 diabetes (the most common form of diabetes). People with Prader-Willi syndrome typically have mild to moderate in

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