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What's different? Part one: Sequencing

centuryofbio.substack.com · 1,514 words · saved by 1 readers

DNA Sequencing is eating the world

Technology is dramatically changing our relationship with biology. After a productive century with many foundational discoveries, our capabilities are beginning to compound in ways that they haven’t before. This is especially true for genetics. Just a matter of decades ago, a PhD in genetics often consisted of sequencing a gene. Now, graduate students sequence genomes, and carry out massive functional studies perturbing every gene that is expressed. What’s different? One simple model that has gained traction is: read, write, edit. This model leans heavily into the analogy of DNA as the…

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