Dialysis-related amyloidosis - UpToDate
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Dialysis-related amyloidosis Authors:Jonathan Kay, MDWajeh Y Qunibi, MD Section Editors:Jeffrey S Berns, MDSteve J Schwab, MD, FACP, FASN Deputy Editor:Eric N Taylor, MD, MSc, FASN Literature review current through: Aug 2026. This topic last updated: Oct 07, 2025. INTRODUCTION Dialysis-related amyloidosis (DRA) is a disabling disease characterized by accumulation and tissue deposition of amyloid fibrils consisting of beta2-microglobulin (beta2-m) in the bone, periarticular structures, and viscera of patients with end-stage kidney disease [1-8]. Beta2-m is a component of the major…
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