How to make an antibody - Works in Progress Magazine

Antibody therapies make up four of the world’s ten best selling drugs. If they were cheaper, they could prevent millions of deaths from rabies, malaria, and dengue.

Diphtheria , the strangling angel, was one of the great killers of children in the 19th century. The infection owes its lethality to a potent toxin released by the bacteria Corynebacterium diphtheriae . Diphtheria toxin destroys the heart, lungs, and liver. In the late stages of disease, the infected are suffocated by a buildup of dead, grey, tissue in their throats. Most victims were children under five; before modern treatments, as many as half of infected babies and toddlers died. There was little parents and doctors could do against the scourge, until biotechnology provided the first answe

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