Muller's ratchet
In evolutionary genetics, Muller's ratchet (named after American geneticist Hermann Joseph Muller, by analogy with a ratchet effect) is a process which, in the absence of recombination (especially in an asexual population), results in an accumulation of irreversible deleterious mutations. That happens because in the absence of recombination, and assuming reverse mutations are rare, offspring bear at least as much mutational load as their parents.
Muller's ratchet - Wikipedia Jump to content From Wikipedia, the free encyclopedia Accumulation of harmful mutations Illustration of chromosome crossover during genetic recombination In evolutionary genetics , Muller's ratchet (named after American geneticist Hermann Joseph Muller , by analogy with a ratchet effect ) is a process which, in the absence of recombination (especially in an asexual population ), results in an accumulation of irreversible deleterious mutations . [ 1 ] [ 2 ] That happens because in the absence of recombination, and assuming reverse mutations are rare,
saved by
related reading
- The Lower Bound to the Evolution of Mutation Rates - PMCncbi.nlm.nih.gov
- Red Queen hypothesis - Wikipediaen.wikipedia.org
- R/K selection theoryen.wikipedia.org
- Thou Art Godshatter — LessWronglesswrong.com
- Selection shadowen.wikipedia.org
- Natural Selection (Stanford Encyclopedia of Philosophy)plato.stanford.edu
- Synonymous substitution - Wikipediaen.wikipedia.org
- The talk: a brief explainer of sexual dimorphismmalmesbury.substack.com
- Directed evolution - Wikipediaen.wikipedia.org
- Gene conversion - Wikipediaen.wikipedia.org
- Sequence homology - Wikipediaen.wikipedia.org
- A minimal scenario for the origin of non-equilibrium orderarxiv.org