Introduction to AAV as a Gene Therapy Vector, Part 1
In two previous posts, we introduced gene therapy, a method for curing genetic diseases by providing healthy copies of defective genes, and Adeno-associated virus (AAV) capsids, the gene therapy delivery system Dyno focuses on.
In two previous posts, we introduced gene therapy, a method for curing genetic diseases by providing healthy copies of defective genes, and Adeno-associated virus (AAV) capsids, the gene therapy delivery system Dyno focuses on. In those posts, we also discussed how natural variants of AAV did not evolve for the specialized functions to which we now seek to apply them, which is why Dyno is applying machine learning and high-throughput techniques to better engineer AAV. This post (the first in a three part series on AAV) provides an overview of AAV as a gene therapy vector, focusing primarily…
saved by
related reading
- Introduction to AAV as a Gene Therapy Vector, Part 2substack.com
- Delivering gene therapy’s promise - Dyno Therapeuticsdynotx.substack.com
- Diversifying gene therapy vectors with machine learningsubstack.com
- Diversifying gene therapy vectors with machine learningsubstack.com
- Dyno Therapeutics: The Capsids You Needcenturyofbio.com
- CRISPR Gene Therapy: Applications, Limitations, and Implications for the Futurencbi.nlm.nih.gov
- Viral vector platforms within the gene therapy landscape | Signal Transduction and Targeted Therapynature.com
- Mnemonic portraits for 19,023 human genes — LessWronglesswrong.com
- Evo 2 Can Design Entire Genomesasimov.press
- Paving the way for agents in biology \ Anthropicanthropic.com
- Asimov — Intelligent Designasimov.com
- Siren Biotechnologysirenbiotechnology.com