Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation: The DECAF Randomized Clinical Trial | Atrial Fibrillation | JAMA | JAMA Network
Wong CX, Cheung CC, Montenegro G, et al. Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation: The DECAF Randomized Clinical Trial. JAMA. Published online November 09, 2025. doi:10.1001/jama.2025.21056 Trial Protocol eMethods eFigure 1. Assessing the Proportional Hazards Assumption for Cox Regression Models eFigure 2. Relative Changes in Coffee Intake eFigure 3. Time to Recurrence of Atrial Fibrillation Only eFigure 4. Time to Recurrence of Atrial Flutter Only eTable 1. Sample Size Calculations eTable 2. Time of Randomization eTable 3. Baseline and Follow Up Antiarrhythmic Medication Use eTable 4. Coffee Consumption Characteristics eTable 5. Consumption of Other Caffeinated Products eTable 6. Clinical Healthcare Encounters During Follow-Up eTable 7. Continuous Recording Devices Use During Follow-Up eTable 8. Recurrence By Site eTable 9. Recurrence Detection Method eTable 10. Paroxysmal or Persistent Episode of Recurrence eTable 11. Primary Endpoint Sensitivity Ana
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