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Mastocytosis - Wikipedia

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Mastocytosis, a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called mastocytes) and CD34+ mast cell precursors.[1] People affected by mastocytosis are susceptible to a variety of symptoms, including itching, hives, and anaphylactic shock, caused by the release of histamine and other pro-inflammatory substances from mast cells.[2] When mast cells undergo degranulation, the substances that are released can cause a number of symptoms that can vary over time and can range in intensity from mild to severe. Because mast cells play a role in allergic reactions, the symptoms of mastocytosis often are similar to the symptoms of an allergic reaction. They may include, but are not limited to[3] There are few qualitative studies about the effects of mastocytosis on daily life. However, a Danish study from 2018 describes the multidimensional impact of the disease on everyday life.[6] Mast cells

Mastocytosis - Wikipedia Jump to content From Wikipedia, the free encyclopedia Immune disorder caused by proliferation of mast cells Medical condition Mastocytosis Other names Clonal bone marrow disorder Micrograph of mastocytosis. Skin biopsy. H&E stain . Specialty Clinical Immunology and Allergy , Oncology , hematology Mastocytosis , a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called mastocytes ) and CD34 + mast cell precursors. [ 1 ] People affected by mastocytosis are susceptible to

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