Brain structural abnormalities in Doberman pinschers with canine compulsive disorder - ScienceDirect

• Parallels exist between canine compulsive disorder (CCD) and human anxiety disorders. • We used MRI to compare brain structure in Dobermans with CCD to healthy controls. • CCD dogs exhibited brain abnormalities similar to those in humans with OCD. • The Doberman CCD model may be useful for studying anxiety disorder etiology. Parallels exist between canine compulsive disorder (CCD) and human anxiety disorders. We used MRI to compare brain structure in Dobermans with CCD to healthy controls. CCD dogs exhibited brain abnormalities similar to those in humans with OCD. The Doberman CCD model may be useful for studying anxiety disorder etiology. Obsessive compulsive disorder (OCD) is a debilitating condition, the etiology of which is poorly understood, in part because it often remains undiagnosed/untreated for a decade or more. Characterizing the etiology of compulsive disorders in animal models may facilitate earlier diagnosis and intervention. Doberman pinschers have a high preval

• Parallels exist between canine compulsive disorder (CCD) and human anxiety disorders. • We used MRI to compare brain structure in Dobermans with CCD to healthy controls. • CCD dogs exhibited brain abnormalities similar to those in humans with OCD. • The Doberman CCD model may be useful for studying anxiety disorder etiology. Parallels exist between canine compulsive disorder (CCD) and human anxiety disorders. We used MRI to compare brain structure in Dobermans with CCD to healthy controls. CCD dogs exhibited brain abnormalities similar to those in humans with OCD. The Doberman CCD mod

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• David Leung