Pharmacokinetics and Pharmacodynamics | Pharmacometrics | Allucent

Home | Services | Clinical Pharmacology Modeling Simulation | Pharmacometrics (PMx), Pharmacokinetics, Pharmacodynamics (PK/PD) Regulatory agencies are responsible for approving all new drugs and for ensuring that all available drugs on the market are effective and safe for human use. Understanding the safety and effectiveness of any drug depends, in large part, on pharmacokinetics (PK), pharmacodynamics (PD), and pharmacometrics (PMx). PK, PD, and pharmacometric modeling and simulation approaches such as population PK (popPK) analyses are used to understand the characteristics of drugs and how they behave in different patient populations. The difference between pharmacokinetics (PK) and pharmacodynamics (PD) is that pharmacokinetics is the movement of drugs through the body, whereas pharmacodynamics is the body’s biological response to drugs. In the simplest terms, pharmacokinetics is what the body does to the drug and pharmacodynamics is what the drug does to the body. PK describes a

saved by

• Gaian Valdegamo