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Neural tuning and representational geometry | Nature Reviews Neuroscience

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Subjects Neural decoding Neural encoding Abstract A central goal of neuroscience is to understand the representations formed by brain activity patterns and their connection to behaviour. The classic approach is to investigate how individual neurons encode stimuli and how their tuning determines the fidelity of the neural representation. Tuning analyses often use the Fisher information to characterize the sensitivity of neural responses to small changes of the stimulus. In recent decades, measurements of large populations of neurons have motivated a complementary approach, which focuses on the

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