US20240344014A1 - 3d shell microelectrode arrays for electrically active organoids - Google Patents
A device for electrically connecting with and holding organoids includes a substrate and a multielectrode array (MEA) attached to said substrate. The MEA includes an electrical bus attached to the substrate, and a plurality of leaflets each having a first end pivotably connected to the electrical bus while remaining portions thereof are free to move relative to the substrate while remaining connected and pivoting at each first end. Each leaflet of the plurality of leaflets includes an electrical wire embedded therein that extends from each respective leaflet into the electrical bus. The MEA has a size that is suitable to electrically connect to and hold an organoid that is between 250 μm to 2 cm while at least one leaflet of the plurality of leaflets is pivoted up away from the substrate so as to securely hold the organoid in place and form a three-dimensional electrical connection with the organoid.
US20240344014A1 - 3d shell microelectrode arrays for electrically active organoids - Google Patents 3d shell microelectrode arrays for electrically active organoids Download PDF Info Publication number US20240344014A1 US20240344014A1 US18/635,861 US202418635861A US2024344014A1 US 20240344014 A1 US20240344014 A1 US 20240344014A1 US 202418635861 A US202418635861 A US 202418635861A US 2024344014 A1 US2024344014 A1 US 2024344014A1 Authority US United States Prior art keywords leaflets organoid substrate shell electrodes Prior art date 2023-04-13 Legal status (The legal status is an assumption and
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