Imaging faster neural dynamics with fast fMRI: A need for updated models of the hemodynamic response - ScienceDirect

Finally, future experimental studies could help illuminate whether there is direct efflux from the glymphatic system to the meningeal lymphatics; if so, techniques developed for modeling peripheral lymphatic vessels (Moore and Bertram, 2018; Margaris and Black, 2012) can be adapted to investigate glymphatic-lymphatic efflux. Although many models have been developed for the hemodynamic link between neuronal activity and local blood volume, often with application to functional MRI (Polimeni and Lewis, 2021), there is a lack of models explicitly linking neuronal activity to CSF flow in physiological conditions. Existing models that are closely related are those that predict CSF flow driven by spreading depolarization during ischemic stroke (Mestre et al., 2020a) and cardiac arrest (Du et al., 2022). Cookies are used by this site. Cookie Settings All content on this site: Copyright © 2024 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and

Finally, future experimental studies could help illuminate whether there is direct efflux from the glymphatic system to the meningeal lymphatics; if so, techniques developed for modeling peripheral lymphatic vessels (Moore and Bertram, 2018; Margaris and Black, 2012) can be adapted to investigate glymphatic-lymphatic efflux. Although many models have been developed for the hemodynamic link between neuronal activity and local blood volume, often with application to functional MRI (Polimeni and Lewis, 2021), there is a lack of models explicitly linking neuronal activity to CSF flow in physiologi