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Synbio25 - A man thinks about building biology

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Synbio25 is a series of essays about the next 25 years of synthetic biology, commemorating my 25th year on this planet, in the 25th year of the 21st century. The future, and what we believe about it, isn't just a technical challenge or a policy debate; it's a collision of grand ideas, personal emotions, and cold incentives. We too often treat ideas as amorphous, independent entities, unconnected to the human experience that created them. I'm the opposite of a dispassionate observer — I'm a passionate participant, playing in this field right now! Synbio25 is a work of love, talking about the future I care about. To me, there is one core problem in all of biotechnology: the vast majority of experiments are done with human hands, manually. Think about that for a second. It is like if a scholar's hand had to write out every book. It is like if we are mining bitcoin on abacuses. We have leveraged great computational power to get better predictivity, but our fundamental productivity is still

Synbio25 - A man thinks about building biology ☰ ↑ Synbio25 (draft1) A man thinks about building biology Preface SECTION 1: THE TECHNO-BIOINDUSTRIAL ECONOMIC MACHINE 1. Introduction Audio 2. Centralization is Coming Audio 3. Too much Tacit Knowledge Audio 4. Bitter Biologists Battle Bioautomation Audio 5. Batching for Economic Efficiency Audio 6. The Bitter Lesson of Synthetic Biology Audio SECTION 2: BLOOD OF THE MACHINE: PEOPLE 7. Holocene Explosion Audio 8. Moral Failure of Genetic Hesitation Audio 9. Transhumanists vs the System Audio 10. Trickle Down Abundance Audio SECTION 3: ME 11. The

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