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The Multilayer Connectome of Caenorhabditis elegans | PLOS Computational Biology

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Affiliation Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom http://orcid.org/0000-0002-4360-5902 Affiliation Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom Affiliations Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom, HHMI Janelia Research Campus, Ashburn, VA, United States of America Affiliation Neurobiology Division, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom http://orcid.org/0000-0001-6078-9312 Affiliation Department of Biological Sciences, Columbia University, New York, NY, United States of America http://orcid.org/0000-0003-1977-0761 Affiliations Department of Psychiatry, University of Cambridge, Cambridge United Kingdom, ImmunoPsychiatry, Alternative Discovery & Development, GlaxoSmithKline R&D, Cambridge United Kingdom

The Multilayer Connectome of Caenorhabditis elegans | PLOS Computational Biology Article Authors Metrics Comments Media Coverage Reader Comments Figures Figures Abstract Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is well established that extrasynaptic volume transmission, especially via monoamines and neuropeptides, is also critical to brain function and occurs primarily outside the synaptic connectome. We have mapped the putative monoamine connections, as well as a subset of neuropeptide connections, in C . elegans based on new and published gene

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