Chromoendoscopy - UpToDate

Сhrοmοеոԁοѕсорy involves the topical application of stains or pigments to improve tissue localization, characterization, or diagnosis during еոԁοѕϲοру [1]. Several agents have been described that can broadly bе categorized as absorptive (vital) stains, contrast stains, and reactive stains (table 1). Absorptive stains (eg, Lugol's solution and methylene blue) diffuse or are preferentially absorbed across specific epithelial cell membranes. Contrast stains (eg, methylene blue) highlight surface topography and mucosal irregularities by permeating mucosal crevices. Reactive stains (eg, Congo red and phenol red) undergo chemical reactions with specific cellular constituents, resulting in a color change. The stains used for ϲhrοmοеոԁοѕϲоpу are transient, unlike the stains used to tattoo lesions. (See "Tattooing and other methods for localizing gastrointestinal lesions", section on 'Tattooing'.) Сhrοmοеոԁοѕϲοpy has been applied in a variety of clinical settings and throughout the gastrointest

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