Older rats show slow modulation of hippocampal theta rhythm during voluntary running - ScienceDirect
• Older rats show slow theta oscillations during voluntary wheel running. • Changes in LT may reflect slower sensorimotor integration in older rats. • MT (6.5–9.5 Hz) mainly modulated theta rhythm in older rats. Older rats show slow theta oscillations during voluntary wheel running. Changes in LT may reflect slower sensorimotor integration in older rats. MT (6.5–9.5 Hz) mainly modulated theta rhythm in older rats. Aging causes brain function degeneration and slows many motor and behavioural responses. The hippocampal theta rhythm (4–12 Hz) is related to cognition and locomotion. However, the findings on aging-related changes in the frequency and amplitude of hippocampal theta oscillations have been inconsistent. We hypothesized that older rats have slower responses in terms of hippocampal theta rhythm during voluntary wheel running than do young adult rats. By simultaneously recording electroencephalography and physical activity (PA), we evaluated theta oscillations in 8-week-old
• Older rats show slow theta oscillations during voluntary wheel running. • Changes in LT may reflect slower sensorimotor integration in older rats. • MT (6.5–9.5 Hz) mainly modulated theta rhythm in older rats. Older rats show slow theta oscillations during voluntary wheel running. Changes in LT may reflect slower sensorimotor integration in older rats. MT (6.5–9.5 Hz) mainly modulated theta rhythm in older rats. Aging causes brain function degeneration and slows many motor and behavioural responses. The hippocampal theta rhythm (4–12 Hz) is related to cognition and locomotion. However,
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