What is cross-presentation and why is it important? - Quora

Cross-presentation is a process in which specialized immune cells, called dendritic cells, are able to take up and present antigens from other cells to activate T cells. This is important because it allows the immune system to recognize and Cross-presentation is the ability of certain antigen-presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells). Cross-priming, the result of this process, describes the naive cytotoxic CD8+T cell stimulation. This process is necessary for immunity against most tumors and against viruses that do not readily infect antigen-presenting cells , or impair dendritic cell normal function . It is also required for induction of cytotoxic immunity by vaccination with protein antigens, for example, tumour vaccination . Cross-presentation is of particular importance, because it permits the presentation of exogenous antigens, which are normally presented by MHC II on the surface of

Cross-presentation is a process in which specialized immune cells, called dendritic cells, are able to take up and present antigens from other cells to activate T cells. This is important because it allows the immune system to recognize and Cross-presentation is the ability of certain antigen-presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells). Cross-priming, the result of this process, describes the naive cytotoxic CD8+T cell stimulation. This process is necessary for immunity against most tumors and against vir