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Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer | Nature

nature.com · 377 words · saved by 1 readers

Functional genomics and lipidomic analyses reveal that sphingolipid synthesis is required for tumour immune evasion and tumour growth in vivo, mediated in part by the impact of glycosphingolipid synthesis on cell surface expression of IFNγ receptors.

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