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Restoring sensorimotor function through intracortical interfaces: progress and looming challenges | Nature Reviews Neuroscience

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Intracortical brain–machine interfaces with sensorimotor cortices are one approach by which a person can exert voluntary control over a prosthetic limb or paralysed muscles. In this Review, Bensmaia and Miller review recent achievements and remaining challenges in the development of intracortical brain–machine interfaces.

Subjects Brain–machine interface Motor control Sensory systems Key Points Brain–machine interface (BMI) control of the kinematics of reaching has progressed dramatically, whereas BMI control of the hand and of the dynamics of movement is still quite limited. Conveying somatosensory feedback is critical for BMIs to be clinically viable, but afferent interfaces are still rather primitive. Biomimicry — that is, attempting to exploit or reproduce natural patterns of neuronal activity — may be an important design criterion. Adaptation, the ability of the nervous system to adapt to novel motor and s

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