ANTIBIOTICS REVIEW

1. Penicillin G (IV) or V (PO) Spectrum: Many strains of Streptococci (Drug of choice for Group A Strep - universally PCN sensitive), minority of Staphylococci (most are resistant) and some Enterococcus, most oral anaerobes, Syphilis (universally PCN sensitive). Used for: Strep throat and other infections due to Group A Strep, Syphilis (for neurosyphilis or pregnant women, must desensitize to PCN), bacteremia/endocarditis due to PCN sensitive Streptococcus, Enterococcus, or Staph aureus (<10% of S.aureus strains are PCN-sensitive), and more. For most situations, generally start with broader antibiotics until pathogen and susceptibilities identified. 2. Aminopenicillins - Ampicillin (IV), Amoxicillin (PO) Spectrum: some Gram positives (Strep, Enterococcus, Listeria) but NOT MSSA, and limited Gram negative coverage. Notable gram negative holes include Klebsiella, Moraxella, and SPICE A organisms. Used for: Upper respiratory infections, sinusitis, otitis media, cellulitis, Listeria i

ANTIBIOTICS REVIEW HOME STANFORD 25 MEDHUB AMION LANE LIBRARY SMARTPAGE SURVIVAL GUIDE REMOTE ACCESS EPIC CPRS advanced Master List Cardiology Endocrinology Gastroenterology General Inpatient Medicine Hematology Infectious Disease Nephrology Neurology Oncology Outpatient & Preventative Medicine Palliative Care Psychiatry Pulmonary/Critical Care Rheumatology ANTIBIOTICS REVIEW TABLE OF CONTENTS ANTIBACTERIALS I. BETA-LACTAMS II. PROTEIN SYNTHESIS INHIBITORS III. FLUOROQUINOLONES IV. SULFONAMIDES = BACTRIM/SEPTRA (TMP/SMX) V. "SUPER GRAM POSITIVE ANTIBIOTICS" VI. "SUPER GRAM NEGATIVE ANTIBIOTICS

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