Dyno Therapeutics: The Capsids You Need
Welcome to The Century of Biology! This newsletter explores data, companies, and ideas from the frontier of biology. You can subscribe for free to have the next post delivered to your inbox: Subscribed Enjoy! 🧬 It’s been seventy years since the image of DNA’s double helical structure entered our collective consciousness. In the subsequent years, we’ve cracked the genetic code, invented powerful DNA sequencers, and discovered molecular machines capable of manipulating and programming nucleic acids. All of this has wide-ranging consequences for life as we know it, but one application is immediately obvious. If some human diseases are caused by genes, can we use the tools of modern genetics to find out which genes are broken and ultimately perform molecular surgery to correct them? The answer is yes, but it’s hard. In total, the FDA has approved thirty-three cell and gene therapy products for clinical use. Of these medicines, only six work by delivering a functional copy of the defective
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