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Skin is amazing, heals very quickly by reprogramming cells for transit

lydianottingham.substack.com · saved by 1 readers

I have previously written about skin on this blog, in the context of transdermal absorption, and how we might be able to pipe all kinds of chemicals down to the bloodstream. I think skin is underrated and pretty interesting because it’s the barrier between us and the rest of the world. Something we discussed at Conduit last night is “can you get me out of my head, and put me back in again?” — i.e. can you help me have a subjective experience located somewhere other than behind-my-eyes without breaking psychological continuity? This is a long-term goal of mind-uploading research. The more proper question is “can you get me out of my skin?” — since cognition takes place all over the body, not just in the brain. I was cooking Christmas dinner a few days ago, and predictably burned myself. I’m very proud of my body for healing up so quickly. But look — this patch of healed skin is paler. What’s going on? I’m not a biologist, but GPT-5.2 directed me to “Wound repair: a showcase for cell pla

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