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New Deep Brain Stimulation Algorithm May Help Personalize Parkinson’s Disease Treatment | Mass General Brigham

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Researchers from Mass General Brigham identified therapeutic targets that may optimize symptom-specific treatment for Parkinson’s disease. Deep brain stimulation (DBS) has shown promise as a treatment for some symptoms of Parkinson’s disease (PD). However, not all symptoms improve equally well with DBS. A better understanding of how different sites of electrical stimulation impact the wide range of motor symptoms associated with PD could help finetune treatment. By studying PD patients at five different centers treated with DBS, investigators from Mass General Brigham created an “atlas” that mapped four major symptoms of PD onto different regions of the brain. Based on these findings, the team created an algorithm capable of generating personalized, symptom-specific DBS treatment plans, which they preliminarily tested in five patients. Findings, published in Nature Communications, demonstrate the algorithm’s potential to improve patients’ symptoms beyond standard-of-care approaches. “T

New Deep Brain Stimulation Algorithm May Help Personalize Parkinson’s Disease Treatment | Mass General Brigham Skip to cookie consent Skip to main content Skip to pause video preview Skip to alerts Skip to pause carousel More alert details New Deep Brain Stimulation Algorithm May Help Personalize Parkinson’s Disease Treatment Jun 4, 2024 7 minute read Technology & Innovation Brain & Nervous System Conditions Research share on facebook share on linkedIn share on X, formerly known as Twitter share by email print article Brain circuits associated with symptom improvements of tremor (green), brady

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