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The MICrONS Project

nature.com · 1,210 words · saved by 1 readers

An unprecedented dataset of high resolution anatomical images of individual cells in mouse visual cortex, mapped on to their responses. This integrated view of function and structure lays a foundation for discovering the computational bases of cortical circuits.

A cubic millimetre might not sound like much — roughly the size of a grain of sand — but to neuroscientists, it is enormous. One cubic millimetre of a mammalian brain contains tens of thousands of neurons with hundreds of millions of connections, or synapses, between them. For most of the history of neuroscience, tracing the detailed connectivity (or connectomics) and measuring activity of neurons at such a large scale was unthinkable. Instead, neuroscientists worked at more manageable scales — even single pairs of connected cells can provide important information, especially when accrued over

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