Revealing protein-protein interactions at the transcriptome scale by sequencing: Molecular Cell

Johnson et al. introduce PROPER-seq for large-scale and time-effective mapping of protein-protein interactions (PPIs) in various cell types based on DNA sequencing. Collected in PROPER v.1.0, PROPER-seq adds more than 200,000 previously uncharacterized PPIs to the reference human protein interactome and provides experimental support to more than 17,000 computationally predicted human PPIs.

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• Madison Ueland