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Egg Transport and Fertilization | GLOWM

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Egg fertilization involves a complex sequence of events that starts with the release of a mature egg from the follicle, continues with the appearance of the two pronuclei after sperm entry, and is completed with the first mitotic division. Understanding the complexities of this process in humans has been limited to a large extent by ethical constraints. However, with the advent of assisted reproductive technologies (ARTs), understanding of the various mechanisms involved in successful fertilization has been greatly enhanced. As ART has developed, so has our understanding of the essentials for human reproductive success. This chapter focuses on what is currently known about human egg transport and fertilization. Egg transport refers to the movement of the oocyte from the moment of expulsion from the ovarian follicle to entry into the distal segment of the fallopian tube before fertilization takes place. Once fertilized in the ampullary segment of the fallopian tube, the embryo spends ab

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