Immune reconstitution inflammatory syndrome - UpToDate

If immune function improves rapidly following the commencement of ART, systemic or local inflammatory reactions may occur at the site or sites of the preexisting infection. This inflammatory reaction is usually self-limited, especially if the preexisting infection is effectively treated. However, long-term sequelae and fatal outcomes may rarely occur, particularly when neurologic structures are involved. This topic focuses on the immunobiology, pathogenesis, and clinical features of IRIS. Topic reviews that discuss when to initiate ART are presented separately. (See "When to initiate antiretroviral therapy in persons with HIV" and "Selecting antiretroviral regimens for treatment-naïve persons with HIV-1: General approach".) TERMS ● Immune recovery disease 网站运行离不开这些 Cookie 且您不能在系统中将其关闭。通常仅根据您所做出的操作（即服务请求）来设置这些 Cookie，如设置隐私偏好、登录或填充表格。您可以将您的浏览器设置为阻止或向您提示这些 Cookie，但可能会导致某些网站功能无法工作。 使用 Cookie，我们可以计算访问量和流量来源，以便衡量和提高我们网站的性能。Cookie 有助于我们了解哪些页面最受欢迎、哪些最不受欢迎，并查看访问者如何浏览网站。这些 Cookie 收集的所有信息都聚合在一起，因

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• 玟均 施