Overview of neonatal brain malformations of the cortex - UpToDate
When managing brain malformations, one should have a basic understanding regarding the developmental process disrupted, the potential causes, the imaging features, and the clinical implications for the child, family, and caregivers. This topic will review these issues, including relevant factors in brain development, magnetic resonance imaging (MRI) sequences for brain malformations, specific types of brain malformations, and their clinical manifestations. Brain malformations will be discussed as isolated, distinct clinical entities. However, patients may have multiple different brain malformations, indicating a more diverse pathological process. The evaluation of brain malformations in the prenatal period is reviewed separately. (See "Prenatal diagnosis of CNS anomalies other than neural tube defects and ventriculomegaly".) NORMAL AND ABNORMAL BRAIN DEVELOPMENT A brief outline of cerebral cortical development, greatly simplified, is presented here [1], which may be helpful in understa
When managing brain malformations, one should have a basic understanding regarding the developmental process disrupted, the potential causes, the imaging features, and the clinical implications for the child, family, and caregivers. This topic will review these issues, including relevant factors in brain development, magnetic resonance imaging (MRI) sequences for brain malformations, specific types of brain malformations, and their clinical manifestations. Brain malformations will be discussed as isolated, distinct clinical entities. However, patients may have multiple different brain malforma
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