On the mechanisms of conjugate vaccines | PNAS

Cover image: Pictured is a primary human hepatocyte spheroid with lipid accumulation (green). Isabel Cordero-Herrera et al. found that nitrite treatment reduced metabolically induced steatosis in human liver cancer cells and primary human hepatocyte spheroids. Nitrate from food sources also prevented liver steatosis in mice that were fed high-fat diets, but not in germ-free mice. The findings suggest that a nitrate-rich diet may help to prevent metabolic disorders, and that host microbiota may play a role in nitrate bioactivation. See the article by Cordero-Herrera et al. on pages 217–226. Image courtesy of Mikael Kozyra. Total number of views and citations for the most recent 6 whole calendar months. See how this article has been cited at scite.ai scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in wh

Cover image: Pictured is a primary human hepatocyte spheroid with lipid accumulation (green). Isabel Cordero-Herrera et al. found that nitrite treatment reduced metabolically induced steatosis in human liver cancer cells and primary human hepatocyte spheroids. Nitrate from food sources also prevented liver steatosis in mice that were fed high-fat diets, but not in germ-free mice. The findings suggest that a nitrate-rich diet may help to prevent metabolic disorders, and that host microbiota may play a role in nitrate bioactivation. See the article by Cordero-Herrera et al. on pages 217–226. Ima