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Aldol Addition - Chemistry LibreTexts

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Along with Claisen condensation reactions, which we will study in the next chapter, aldol additions are responsible for most of the carbon-carbon bond forming events that occur in a living cell. …

We arrive now at one of the most important mechanisms in metabolism: the aldol addition. Along with Claisen condensation reactions, which we will study in the next chapter, aldol additions are responsible for most of the carbon-carbon bond forming events that occur in a living cell. Because biomolecules are built upon a framework of carbon-carbon bonds, it is difficult to overstate the importance of aldol addition and Claisen condensation reactions in the chemistry of living things! Overview of the aldol addition reaction Consider the potential pathways available to a reactive enolate intermed

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