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Targeting UGCG overcomes resistance to lysosomal autophagy inhibition - PMC

pmc.ncbi.nlm.nih.gov · 23 words · saved by 1 readers

Lysosomal autophagy inhibition (LAI) with hydroxychloroquine or DC661 can enhance cancer therapy, but tumor regrowth is common. To elucidate LAI resistance, proteomics and immunoblotting demonstrated that LAI induced lipid metabolism enzymes in ...

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