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GBA Variants and Parkinson Disease: Mechanisms and Treatments - PMC
pmc.ncbi.nlm.nih.gov · 23 words · saved by 1 readers
The GBA gene encodes for the lysosomal enzyme glucocerebrosidase (GCase), which maintains glycosphingolipid homeostasis. Approximately 5–15% of PD patients have mutations in the GBA gene, making it numerically the most important genetic risk factor ...
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